Glutathione (GSH) Glutathione (GSH), the prominent non-protein intracellular thiol compound, is a tripeptide made from the amino acids glycine, cysteine, and glutamic acid and it is the main player in antioxidant defense against reactive oxygen species (ROS) and electrophiles
Increases in oxidative stress may shift homocysteine metabolism towards trans-sulfuration to increase hepatic production of reduced glutathione
Your body needs 50% longer to clear the same amount of alcohol
The ADRs of interest include suicidal ideation, self-injurious ideation, suicidal behaviors, and self-injurious behaviors (see Additional file 1: Table S1 for a detailed list), which are homogenously attributed to a high-level group term (HLGT) named suicidal and self-injurious behavior by MedDRA (version 26.0)
PMID 20599753
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