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KEY TAKEAWAY: Month 1 success comes from establishing the right habits before symptoms peak
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15 reflects a different mechanism, reported recently, in which GLP-1 induces rapid post-translational activation of glucokinase 41, 42
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Nevertheless, the beneficial testicular effects of these emerging therapies appear to vary according to basal levels of androgens, as emerged in a recent prospective cohort study where the exenatide-based therapy did not significantly change FT levels in diabetic men without hypogonadism [159] , thus supporting a relevant role of incretin mimetics on male HPG axis, particularly in hypogonadism
