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Patients may notice physical changes, such as abdominal swelling, as well as sensations of discomfort or fullness

[Accessed 26 January 2026] Once-weekly semaglutide 72 mg in adults with obesity (STEP UP): a randomised, controlled, phase 3b trial
Taste disturbances have been reported with various GLP-1 medications, though the frequency varies between products
Its profound impact on tissue regeneration and wound healing mirrors the intended effects of many banned substances

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