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Autophagy: cellular and molecular mechanisms
These factors can lead to flare-ups or worsening of symptoms
For example, melatonin has been found to stimulate the -secretase cleavage of APP in cultured neuronal and non-neuronal cells [52] via upregulation of the nonamyloidogenic ADAM10 and ADAM17 proteases
A: Neither compound is approved by the FDA for human or veterinary use
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Likewise, a balanced ROS production and ROS-dependent signaling seem to be favorable for normal growth behavior and cellular differentiation
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