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fluorescein, fluorescein isothiocyanate dextrans) that penetrate the blood-brain barrier to a limited degree based on molecular weight

In mice lacking SGLT1, the reduction in postprandial glucose response mediated by a single administration of metformin is attenuated, but not in mice lacking glucose transporter 2 (GLUT2)

Proton pump inhibitors (omeprazole, pantoprazole) reduce magnesium absorption in the gut

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Marso SP, Bain SC, Consoli A, Eliaschewitz FG, Jodar E, Leiter LA, et al

This could theoretically affect DNA methylation, gene expression, and other processes dependent on methylation