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10.1001/jama.2017.18391 JAMA

Activation of AMPK in the hypothalamus results in altered fatty acid metabolism and increased mitochondrial fatty acid oxidation which ultimately results in increased release of NPY and AgRP leading to an increased desire for food intake

They are not to be classified as a drug, food, cosmetic, or medicinal product and must not be mislabelled or used as such

Ozempic, on the other hand, has a well-established track record and a strong safety profile

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