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Both start at a dose intended to be well below the therapeutic threshold, primarily serving as an acclimation period for the GI system

PMID: 232 WojtukiewiczMZRekMMKarpowiczKGrskaMPolityskaBWojtukiewiczAMet al

Because oral glutathione must pass through the complex environment of the stomach and intestines, it can occasionally irritate the delicate lining of the digestive tract

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Retatrutide is an investigational compound that is not approved by the FDA for human use