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The best route depends on safety, diagnosis, and the clinicians plan
The commonly recommended timing, morning on an empty stomach 30-60 minutes before eating, maximizes fat oxidation effects but may increase nausea in sensitive individuals
It also helps the body convert food into glucose, giving you the energy you need to get through the day
Pre-existing inborn errors of sulfur-amino-acid metabolism (e.g., homocystinuria) represent an absolute contraindication because parenteral methionine can exacerbate elevated homocysteine concentrations and associated thrombotic risk
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