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With respect to cell death, induction of p21 FL modestly delayed the onset of erastin2-induced death alone, and to a greater extent when combined with nutlin-3, consistent with an independent requirement for both p53 and p21 in the suppression of ferroptosis (Fig 2F)

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Then, 5 l of reconstituted samples, kept at 6 C in the autosampler, were injected into the LCMS/MS system at a flow rate of 0.350 ml min 1 with 57% mobile phase A

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