Post-Approval Experience: While all adverse reactions are not reported, the following adverse reactions are based on voluntary post-approval reporting for LEGEND Injectable Solution: Following Intravenous use: Occasional depression, lethargy, and fever
These include: Nausea Vomiting Diarrhoea Constipation Decreased appetite (which, whilst therapeutically intended, can occasionally be excessive) Injection-site reactions (such as redness, bruising, or discomfort at the injection site) These effects were generally mild to moderate in severity and most frequently occurred during the dose-escalation phase of treatment, tending to diminish over time
Orexin (hypoocretin) from hypothalamus and is involved in regulating wakefulness and appetite
GLP-1RA vs
A detailed thyroid history is essential, including diagnosis date, current levothyroxine dosage, recent TSH and free T4 levels, presence of thyroid nodules, history of thyroid surgery or radioactive iodine treatment, and any family history of thyroid cancer or MEN 2 syndrome
Highly recommended for those who want to improve their performance in workouts that involve muscle fatigue
