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Current data indicate that over 90% of intravenously administered nanoparticles are captured by the mononuclear phagocyte system within 24 h, resulting in a substantial reduction in renal accumulation efficiency, typically less than 5% of the administered dose
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Mean nuclear GFP intensity was used as a quantification for Nrf2-GFP, integrated cytoplasmic GFP intensity was used as a quantification for Srxn1-GFP and amount of cytoplasmic foci per cell was used as a quantification for Keap1-GFP
It has shown potential for supporting the management of chronic gastrointestinal conditions, such as inflammatory bowel diseases (IBD), including ulcerative colitis (UC)