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Skin Aging and Collagen Loss Skin aging involves several structural changes: reduced collagen synthesis increased collagen degradation decreased elastin integrity slower cellular turnover These processes contribute to wrinkles, skin laxity, and reduced resilience

Hum Ecol Risk Assess 13(5):11471155 Aksoy M, Ozaslan MS, Kfrevioglu I (2016) Purification of glutathione S -transferase from Van Lake fish ( Chalcalburnus tarichii Pallas) muscle and investigation of some metal ions effect on enzyme activity

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These results suggested that the regulatory signaling of cell cycle arrest and apoptotic resistance were enhanced in keloid fibroblasts