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Funding PE was funded by the Medical Research Council and now by Higher Education Funding Council for England (HEFCE)

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First, B12 supplementation may help offset potential nutritional deficiencies caused by reduced food intake on GLP-1 therapy

These findings suggest that GLP treatment is associated with higher resting cardiovascular activation and reduced parasympathetic activity , indicating increased physiological load reported across studies[1]

If you are extremely sensitive and find that taking the supplement on a completely empty stomach causes mild nausea, clinical evidence suggests pairing it with a very small, light snack (such as a few bites of fruit or a cracker) can mitigate digestive discomfort while still preserving the stability of the acetylated molecule