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Efficacy and safety of switching to once-weekly semaglutide from dulaglutide or exenatide once weekly in patients with type 2 diabetes (SUSTAIN 7): a multicentre, open-label, randomised, phase 3b trial
Unlike single-pathway peptides, retatrutide aims to control multiple metabolic triggers at once, creating more sustainable shifts in hunger, cravings, nutrient use, and basal metabolic rate
2017;12:e0180989
What are the side effects of weight-loss injections
Two brain regions that have GLP-1 receptors present are the ventral tegmental area and nucleus accumbens, which happen to be critical in the development of substance use disorders, where addictive substances hijack natural reward pathways, leading to compulsive behaviors
doi: 10.1016/S0140-6736(19)31149-3 18 GersteinHCSattarNRosenstockJRamasundarahettigeCPratleyRELopesRDet al
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