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Most common side effects are gastrointestinal such as mild nausea, soft stools or diarrhea

It was first developed at the University of Arizona in the 1980s and 1990s

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However, a 9-year follow-up study of Finnish male smokers aged 5069 years [51] showed that when compared with weight-stable subjects, subjects with greater weight fluctuations had a significantly increased risk of type 2 diabetes

10.1186/s12906-017-2044-1 BMC Complement Altern Med

This suggests that the improvements in metabolic parameters were primarily driven by the modulation of lipid and glucose metabolism, rather than the suppression of inflammation