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Anecdotal reports from some patients have suggested changes in libido during treatment with GLP-1 receptor agonists, though these observations have not been systematically studied or confirmed in controlled research
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both molecules are contraindicated in patients with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia type 2 (MEN 2)
For many patients, semaglutide is intended as part of a longer-term strategy that may include nutrition, physical activity, and behavioral support
doi: 10.3390/nu13103432 7
Furthermore, the risk of hypoglycaemiaa major challenge when using insulinis reportedly lower with GLP-1RAs, given their glucose-dependent mechanism of modulating insulin release and glucagon suppression [25]
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