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The recommended discontinuation timeline differs by medication

Current Availability of Oral GLP-1 Medications Benefits and Challenges Compared to Injections What This Means for Patients, Providers, and the Future Conclusion FAQs What is a GLP-1 Pill and How Does it Work

A 2026 analysis projected a 1.9-year gain in life expectancy with semaglutide treatment (van Sloten et al., 2026, PMID: 41800807)

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Furthermore, individuals aged 1849, 5069, and 70 showed increased risks of 101%, 78%, and 71%, respectively, for any psychiatric disease when using GLP-1 RAs compared to non-users

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