10.1038/s41443-024-00895-6
Some studies have shown that GLP-1RAs act on the hypothalamus to promote satiety and reduce food intake, inhibit gastric emptying [52], thereby leading to weight loss and potentially improving upper airway collapsibility
Semaglutide promotes the proliferation and osteogenic differentiation of bone-derived mesenchymal stem cells through activation of the Wnt/LRP5/beta-catenin signaling pathway
Bottom Line: People on GLP-1s Should Be Monitored for Health Changes Experts say the findings should not discourage appropriate use of GLP-1 medications, which provide significant benefits for many people with diabetes and obesity, including improvements in heart health, kidney function, and liver disease
It's important to note that the study was small and the patients were mostly white and privately insured, meaning the results may not apply to everyone
10.1016/j.chest.2019.10.009 Chest