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Gene expression studies using microarray analysis reported that GHK-Cu at low nanomolar concentrations influenced the expression of over 4,000 human genes in fibroblast models, including upregulation of collagen I, collagen III, and elastin synthesis, and modulation of matrix metalloproteinase activity (Pickart and Margolina, Symmetry 2018)

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View image online ( stylized scientific illustration of hormone receptors For patients with type 2 diabetes and established cardiovascular disease, incretin-based therapy that targets both the GLP-1 and GIP gut hormones is associated with significantly greater cardiorenal benefits than therapy that targets GLP-1 alone

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Koutnik AP, DAgostino DP, Egan B

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