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The FDA advises against their use in people with a personal or family history of medullary thyroid carcinoma (MTC), in those with Multiple Endocrine Neoplasia type 2 (MEN2), or in patients with severe gastroparesis or past serious allergic reactions

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Additionally, anecdotal evidence and individual case studies have hinted at benefits in areas such as autism spectrum disorders and chronic fatigue syndrome 2

McCall McPhereson: Yeah, so when people have lost true endogenous thyroid function, when their thyroid gland is no longer functioning, adequately secreting hormones