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Description

The metabolic features include iron overload, ROS buildup, and the inactivation of the antioxidant enzyme GPX4 [51,55]

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Autophagy regulates ferroptosis through mechanisms such as mitophagy and ferritinophagy (200, 235)

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However, practical experience suggests both approaches produce beneficial outcomes, with the choice often driven by convenience rather than optimization concerns

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NAD+ precursors are studied for supplying metabolic substrates

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J., Forman, D., Howard, G

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We adjust the dose based on how well theyre doing and lab results

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