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3.2 Preclinical studies of ferroptosis in neurodegenerative diseases 3.2.1 Ferroptosis and alzheimers disease AD is a prevalent and progressive neurodegenerative disorder, characterized by the accumulation of extracellular -amyloid (A) plaques and intracellular neurofibrillary tangles formed by hyperphosphorylated Tau protein, accompanied by excessive neuroinflammation, synaptic dysfunction, and neuronal loss, ultimately resulting in impairments in language, judgment, and executive function, and even leading to the loss of independent living ability (Hooper et al., 2025)

in vitro testing is generally not recommended based on poor sensitivity

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Fact: Supplementing with glutathione provides a "ready-to-use" pool of antioxidants that can reduce the immediate burden on your liver, but it does not "turn off" your body's natural production