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It belongs to the biguanide class of drugs and works by reducing glucose production in the liver, improving insulin sensitivity in the body, and decreasing intestinal absorption of glucose
Ferdinand KC, White WB, Calhoun DA, et al
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The GSTK1/RETREG1 complex conferred protection against diabetic tubular damage and kidney injury via modulating ER stress and apoptosis through the induction of reticulophagy, thereby revealing that maintaining ER homeostasis is crucial for the control of apoptosis (37)
The Kaplan-Meier curves in Figure 5D show the cumulative incidence of tirzepatide ADEs in the sex subgroups, with no significant differences observed
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