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Notably, Byetta was not approved as monotherapy initially (only as add-on), and it carried precautions about pancreatitis (we discuss safety later) and a note that it wasnt a substitute for insulin in type 1 diabetes
10.1016/j.bmc.2013.09.016 59
these agents should be used with caution in patients with existing cardiac conditions [15] [16] Bullous pemphigoid : A rare skin blistering condition has been reported with long-term use of some gliptins, as noted in MHRA safety communications
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