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Akhigbe R, Ajayi A
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At the same time, melatonin treatment significantly inhibited the oxaliplatin-induced increase in the mRNA expression of cytokines such as interleukin-1 (IL-1), tumor necrosis factor- (TNF-), monocyte chemoattractant protein-1 (MCP-1), and monocyte inflammatory protein-1 (MIP-1) in the spinal dorsal horn [48]
For patients with diabetes, persistent sugar cravings accompanied by elevated blood glucose readings may indicate inadequate glycemic control requiring treatment intensification
As the development of a sublingual delivery of biological GLP-1 receptor agonists heralds a new era in chronic disease management, the technology is poised to significantly improve quality of life for millions of patients worldwide
While short-term efficacy is well-documented, concerns remain about the long-term impact of prolonged GLP-1 receptor activation, particularly in non-diabetic populations
