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2.2 Treatment and tolerance tests Male and female mice (22- to 25-week-old) were placed in clean cages and food withheld for five hours
Hydroxytyrosol [64], resveratrol [65], as well as DHA [45] supplementation increased BDNF expression in the brain of the ES-exposed offspring, potentially contributing to the beneficial effects on the ES-induced cognitive decline observed
However, the extent of these benefits across different age groups, particularly regarding age-related cognitive decline, remains to be explored
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