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Pancreatitis Acute pancreatitis has occurred in patients treated with GLP-1 agonists, including tirzepatide
Notably, tirzepatide showed greater HbA1c reductions compared with other GLP-1 RAs, supported by high-certainty evidence
Also, sadly enough, there also are many types of (chronic) diseases that require B12 injections, such as Pernicious Anemia, people with Crohns, celiac, and people with intestinal imbalances, such as intestinal tapeworms and excessive bacterial growth
Despite the pleiotropic properties of GLP-1, including its insulinotropic effect found in rats, pigs, and humans, its extremely short plasma half-life of less than 2 minutes constituted a huge brick wall in the path of GLP-1 to be developed as a glucose-lowering medication
10.1038/nm.3128 46 KimE
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