& Zwozdziak, B
Semaglutide works by slowing stomach emptying and reducing hunger signals, which often leads to weight lossand that weight loss typically improves blood pressure
It also means reaching clinically meaningful thresholds, like a 10% or 20% reduction, sooner, which translates to earlier improvements in comorbidities like type 2 diabetes, hypertension, and sleep apnea
Pernicious anaemia , an autoimmune condition affecting intrinsic factor production in the stomach, represents the most common indication
Horowitz M, Rayner CK, Marathe CS, Wu T, Jones KL (2020) Glucagon-like peptide-1 receptor agonists and the appropriate measurement of gastric emptying
Comparison with previously reported responses to different GLP1 multi-agonists in other (non-androgenic) models of obesity (see Suppl