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The first is that tirzepatide is a partial, biased GLP-1R agonist, a profile that confers superior glucose and weight lowering in preclinical models (4751)

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Weight and anthropometric outcomes Percentage weight loss The average percentage weight-loss trajectories with semaglutide and placebo over 4 years of observation are shown in Fig

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Role of insulin-like growth factor-1 (IGF-1) pathway in the pathogenesis of Graves orbitopathy