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HUBERMAN: And this is very important to understand because unlike a lot of our discussion on this podcast about dopamine or about specific hormones like testosterone or estrogen, when we talk about peptides, especially therapeutic peptides, oftentimes we're talking about a single peptide that does a bunch of different things depending on the cell type, the time of day or night that that peptide is present, and even the different so-called downstream effects of the peptide

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In addition, the predictive performance of the final model was assessed by prediction-corrected visual predictive check (VPC) plots

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Jain (AstraZeneca, Cambridge, UK) for critical review and comments on the manuscript during preparation

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