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Patients with certain genetic profiles show higher sensitivity to GLP-1 effects, meaning they reach therapeutic results at lower doses and suffer more severe side effects if over-dosed

Salazar CE, Patil MK, Aihie O, Cruz N, Nambudiri VE

Second, calculate the injection volume: divide the desired dose (in mcg) by the concentration (in mcg/mL)

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The main difference is the amount of medication used, with Trulicity rising to 4.5mg if necessary and Wegovy up to 2.4mg