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631,632 Cao et al

Activation of ROS/MAPKs/NF-B/NLRP3 and inhibition of efferocytosis in osteoclast-mediated diabetic osteoporosis

Skitzki JJ, Repasky EA, Evans SS

Acceleration of glutathione efflux and inhibition of gamma-glutamyltranspeptidase sensitize metastatic B16 melanoma cells to endothelium-induced cytotoxicity

Besides exercise and nutrition, the paper also highlights weight loss, caloric restriction, and metabolic flexibility as key strategies to reduce oxidative load and improve glutathione recycling

In these habitats, limited food driven by sea urchin herbivory reciprocally affects sea urchin physiology, yet the metabolic pathways enabling survival in the starvation conditions remain poorly understood