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Dimethyl fumarate (DMF), an FDA-approved drug prescribed for the treatment of multiple sclerosis (55, 56), activates NRF2 by disrupting its interaction with KEAP1 ( Figure 7A ), allowing NRF2 to translocate to the nucleus and become transcriptionally active (5557)

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There may also be a peripheral component

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Fat pads in the face provide structure and volume to the face

Safe Disposal of Unused or Expired Solution Unused or expired reconstituted retatrutide should be returned to a community pharmacy or disposed of as clinical/pharmaceutical waste per HTM 07-01