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Rational design using sequence information only produces a peptide that binds to the intrinsically disordered region of p53
PubChem CID: 9941957 PubChem SID: 329830514 CAS Number: 137525-51-0
doi: 10.1038/nm.3822 140 OtterSLammertE
Request an Appointment Understanding GLP-1 and Why It Matters Glucagon-Like Peptide-1 (GLP-1) is a naturally occurring hormone that plays a central role in metabolic function
The peptide consists of three amino acidsglycine, histidine, and lysinearranged in a specific sequence that enables strong copper binding (log K = 16.44)
As a result, the expression of transgenes encoded within the adenoviral vectors is shortened (14)
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