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Frye et al., 2018
L-cells sit along the distal small intestine and colon
Published data from growth hormone axis studies demonstrates that this pulsatile delivery pattern more accurately mimics endogenous GHRH secretion rhythms compared to continuous infusion models
However, it can also be a symptom of gastrointestinal cancer
Important FDA Disclosure About Compounded GLP-1 Medications Compounded GLP-1 medications are not FDA-approved
Individual variability in treatment response is well-documented, with some patients achieving less than 5% body weight reduction despite proper use
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