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By morning, the effect has passed
The increased oxidative stress seems to be the second hit in the progression from NAFL to NASH: the increase in ROS and consequently in lipid peroxidation has been associated to hepatocellular damage, inflammation, and eventual fibrosis due to the activation of hepatic stellate cells
In this case report, a multimodal program including a ketogenic diet and nutritional supplements was followed for 22 months
(Anton 2003)
It is present in all cells at millimolar concentrations (110 mM)orders of magnitude higher than any other intracellular antioxidant
Familial aggregation and genetics
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