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doi: 10.1016/j.neuropharm.2010.01.004 155 RouaultA

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The manufacturer, Pfizer , recently reported results for their Phase 2b trial

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This process involves several intricate steps and relies on various enzymes, coenzymes and other molecules

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Using a murine model of HSV-1 encephalitis our laboratory has shown that intranasal delivery of HSV induces a robust activation of brain microglial cells, production of proinflammatory mediators, and focal tissue damage which, if left untreated, can result in prolonged brain inflammation, and compromised brain function or death [15]

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