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GPx activity and neuroprotective effects of H 2 O 2 It is generally agreed that ischemic insult facilitates an excessive generation of hydroxyl radicals and, therefore, GPxs have an important role in the defense against H 2 O 2 -induced damage
Compounds metabolized by CYP450 enzymes, especially those producing reactive metabolites, are linked to cellular stress and a heightened risk of idiosyncratic DILI
doi: 10.3390/vaccines11050934 84 YasudaSSuzukiSYanagisawaSMoritaHHaisaASatomuraAet al
doi: 10.1093/NAR/GKAA407
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