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The enema induces bowel movements to clear the colon, but normal bowel function should resume afterward
A pharmaceutical-grade compounding setup with proper buffering and cold-chain storage produces stable formulations
The population in SELECT was different that STEP-1 and SUMOUNT 1, with 90.1% of patients on lipid-lowering therapy and a much lower baseline LDL-C of 78 mg/dL compared to 111 mg/dL and 110 mg/dL in STEP-1 and SURMOUNT 1 respectively [33, 35, 48]
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