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Accessed on May 14, 2025 at MedlinePlus

Gradually increasing the dosage is intended to minimize side effects and help the body adjust to the medication's effects, including constipation

Type 2 diabetes genetic loci informed by multi-trait associations point to disease mechanisms and subtypes: a soft clustering analysis

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A comprehensive meta-analysis of extensive studies from 165 RCTs with 122,072 with T2DM patients demonstrated that alogliptin significantly reduces the likelihood of gastrointestinal side effects [71]