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Semaglutide is indicated, in combination with a reduced calorie diet and increased physical activity, to reduce excess body weight and maintain weight reduction long term in adults and pediatric patients aged 12 and older with obesity, and in adults with overweight plus at least one weight-related comorbid condition

Author contributions JM-M: conceptualization, data curation writing-original draft and writing-review & editing

It makes dietary change more achievable, but it does not replace it

If you take a daily B12 supplement or multivitamin and your levels are mildly elevated (900 to 1,200 pg/mL), the most likely explanation is the supplement

Around 70% of American adults are obese or overweight, and they have an increased risk of premature death and a variety of health problems, including heart attack and stroke

PMID: 16539679 Khvatova EM, Samartzev VN, Zagoskin PP, Prudchenko IA, Mikhaleva II (2003) Delta sleep inducing peptide (DSIP): effect on respiration activity in rat brain mitochondria and stress protective potency under experimental hypoxia