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GLP-1's primary functions include: Enhancing insulin secretion in response to glucose Suppressing inappropriate glucagon release Delaying gastric emptying Promoting satiety and reducing appetite Understanding GLP-1's role is fundamental when evaluating whether dietary interventions, such as allulose consumption, might influence incretin hormone activity or complement GLP-1-based therapies

In the Phase 2 trial, participants on the highest dose of retatrutide (12mg) experienced a mean increase in resting heart rate of approximately 4 to 6 beats per minute

Around exercise: Some users prefer injecting 30-60 minutes before workouts to maximize fat utilization during training