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This review highlights that various forms of choline supplementation may support memory and cognitive function
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routine use in replete patients has limited evidence
Methylcobalamin is also contraindicated in patients with cobalt hypersensitivity because methylcobalamin contains cobalt
Adverse reactions reported following methylcobalamin administration include headache, infection, nausea/vomiting, paresthesias, and rhinitis
repletion reverses hematologic symptoms within days and neurologic sequelae over weeks, reflecting differential tissue turnover
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