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J., Park, J
Beilstein/REAXYS Number: 1718700
In vitro analysis, using COS-7 cells [134] and motor neuron-like NSC-34 cells [135] has shown that mSOD1 can be secreted, and in vivo analysis appears to support these observations [134], but extracellular mSOD1 alone does not appear to be directly toxic to motor neurons [126]
These first two requirements must both be met if you want to set-up an HSA, according to the IRS
These aldehydes are highly reactive compounds because they have electrophilic properties, they are less volatile than hydroperoxides, and can diffuse from the place of origin and express their reactivity through biotransformation and adduction to biomolecules (proteins, DNA)
Dec 2019;170:113662
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