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Adding TB-500 increases both cost and complexity, so it makes sense to reserve the stack for more challenging cases
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suggests that TB-500 may interact with cell movement as it binds globular actin (G-actin) and may modulate how actin filaments assemble to plausibly make endothelial cells more able to change shape, migrate, and form multicellular structures
Because less of the peptide is likely to be degraded in the stomach during oral studies, researchers may find that different dosing models are required to achieve the same systemic exposure compared to the acetate form
