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When antioxidant capacity, particularly glutathione peroxidase (GPx) activity, is insufficient, oxidative stress can accumulate and damage thyroid proteins, including thyroid peroxidase (TPO)
Glutathione is the liver's primary endogenous antioxidant, comprising three amino acidsglutamic acid, cysteine, and glycine
Radtke et al., 2012)
33 Marked regional variation exists between EAC and ESCC
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