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Turino GM, Ma S, Lin YY, Cantor JO

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By contrast, 7-hydroxymitragynine (7-OH), while also labeled a partial agonist, is highly potent at the same receptors and produces dose-dependent respiratory depression and dependence signals in animal studies

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Taking time to eat slowly and stopping when you feel comfortably satisfiedrather than fullcan help prevent discomfort

Since bipolar disorder is also linked to imbalances in neurotransmitters, there could be a potential overlap in how these mechanisms work