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evaluated the effects of inhibitors of necroptosis, apoptosis, and ferroptosis (Necrostatin-1, z-VAD-FMK, and Fer-1, accordingly) on primary cultured RGCs suffering RIR injury, with Fer-1 conferring the best efficacy (9)

Careful monitoring, conservative scheduling, and disciplined records are what make the safety profile interpretable

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Peptide approaches aim for slower, self-regulated change