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Gallbladder Disease: Rapid weight loss combined with altered gut motility can increase the risk of gallstones or cholecystitis (gallbladder inflammation), which presents as sharp pain in the upper right portion of the abdomen
Ozempic and other glucagon-like peptide 1 receptor agonists have been associated with an increased risk of gallbladder issues, such as gallstones and cholecystitis
In people with type 2 diabetes, semaglutide prompts the pancreas to release insulin when blood glucose is high , and stops the pancreas from releasing glucagon (which raises blood sugar) when it is not needed
For compounded peptides, exposure over 24 hours should prompt consideration of replacement
Patients who experience new symptoms should discuss them with their healthcare provider rather than making assumptions or attempting to manage concerns on their own
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