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10.1016/j.kint.2020.09.037 28 DagarN.KaleA.SteigerS.AndersH

Paulis L, Rajkovicova R, Simko F

The first scaffold is a tertiary amine that acquires a positive charge in response to an acidic component in endosomes and lysosomes that promotes membrane destabilization and subsequent endosomal escape

An increase in the GSSG/GSH ratio in mouse islets and INS1 cells during this process suggests that an oxidative environment is required for insulin secretion [31]

Modulating effects of the extracellular sequence of the human insulin-like growth factor I receptor on its transforming and tumorigenic potential

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